{"id":45710,"date":"2026-07-13T12:00:00","date_gmt":"2026-07-13T12:00:00","guid":{"rendered":"http:\/\/www.prnasia.com\/story\/archive\/5002667_CN02667_0"},"modified":"2026-07-13T12:00:00","modified_gmt":"2026-07-13T12:00:00","slug":"delonix-bioworks-announces-first-participant-dosed-in-phase-1-clinical-trial-of-next-generation-menb-omv-vaccine-dx-104-in-china","status":"publish","type":"post","link":"https:\/\/transmediavictoria.net.au\/?p=45710","title":{"rendered":"Delonix Bioworks Announces First Participant Dosed in Phase 1 Clinical Trial of Next-Generation MenB OMV Vaccine DX-104 in China"},"content":{"rendered":"

SHANGHAI<\/span>, July 13, 2026<\/span> \/PRNewswire\/ — Delonix Bioworks, a clinical-stage biotechnology company pioneering genetically engineered bacterial vaccines, today announced that the first participant has been dosed in its Phase 1 clinical trial of DX-104 in China. DX-104 is an innovative Group B meningococcal (MenB) vaccine candidate developed using the company’s proprietary OMV Plus\u00ae platform. This milestone marks a significant step in the concurrent global development of DX-104, following the initiation and ongoing progress of the DX-104 First-in-Human Phase 1 trial in Australia.<\/p>\n

The Phase 1 trial in China is a randomized, double-blind, placebo-controlled study designed to evaluate the safety and immunogenicity of DX-104 in healthy participants aged 2 to 59 years.<\/p>\n

“The concurrent execution of Phase 1 trials in Australia and China enables the generation of clinical data across diverse populations, providing robust validation of our OMV Plus\u00ae platform’s distinct advantages and global development potential,” said Dr. Qiubin Lin, Founder and CEO of Delonix Bioworks. “As MenB remains a significant global health threat, DX-104 is designed to deliver a next-generation vaccine with broader protection, improved tolerability, and enhanced global accessibility.<\/p>\n

About Invasive Meningococcal Disease and MenB<\/b><\/p>\n

Invasive meningococcal disease (IMD) is a devastating, rapidly progressing bacterial infection. Globally, serogroup B (MenB) has become the leading cause of IMD, responsible for approximately 50% of cases with a steadily rising prevalence. While established global vaccines have validated the significant market demand, critical gaps remain regarding strain coverage, manufacturing complexity, and equitable access. Currently, no MenB vaccine is approved in China, representing a critical public health gap. According to Frost & Sullivan, the market potential for MenB vaccines in China is projected to reach RMB 4.7 billion by 2035.<\/p>\n

About DX-104\uff08MenB OMV vaccine\uff09<\/b><\/p>\n

DX-104 is a Group B meningococcal OMV vaccine candidate leveraging Delonix’s proprietary OMV Plus\u00ae technology platform. It utilizes genetically engineered outer membrane vesicles (OMVs) to enable precise antigen presentation. DX-104 is designed to address the limitations of existing MenB vaccines in strain coverage, manufacturing complexity, and global accessibility, aiming to fulfill the significant global unmet medical need in MenB prevention.<\/p>\n

About Delonix Bioworks<\/b><\/p>\n

Delonix Bioworks is a clinical-stage biotechnology company at the forefront of developing next-generation genetically engineered bacterial vaccines. Leveraging its proprietary OMV Plus\u2122 platform, the company produces high-yield, cost-effective, and precisely engineered outer membrane vesicles (OMVs) designed for superior antigen presentation and immunogenicity. Delonix is dedicated to advancing a robust pipeline of first-in-class and best-in-class programs addressing critical unmet needs, including vaccines for Meningococcal B<\/i>, pertussis<\/i>, gonorrhoeae<\/i>, and K. pneumoniae<\/i>.<\/p>\n

For more information, please visit https:\/\/delonixbio.com\/<\/b><\/a> or contact BD@delonixbio.com<\/b><\/a>.<\/p>\n

Disclaimer: This press release is intended to present factual statements regarding the Company’s products, technological advancements, and business collaborations, etc. Certain statements herein concerning new technology performance, clinical trial results, or strategic cooperation frameworks may involve uncertainties and risks. The Company expressly disclaims any guarantee of future performance based on this press release or the information stated therein.<\/p>\n","protected":false},"excerpt":{"rendered":"

SHANGHAI, July 13, 2026 \/PRNewswire\/ — Delonix Bioworks, a clinical-stage biotechnology company pioneering genetically engineered bacterial vaccines, today announced that the first participant has been dosed in its Phase 1 clinical trial of DX-104 in China. DX-104 is an innovative Group B meningococcal (MenB) vaccine candidate developed using the company’s proprietary OMV Plus\u00ae platform. This […]<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"class_list":["post-45710","post","type-post","status-publish","format-standard","hentry","category-business-news"],"yoast_head":"\nDelonix Bioworks Announces First Participant Dosed in Phase 1 Clinical Trial of Next-Generation MenB OMV Vaccine DX-104 in China - My Blog<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/transmediavictoria.net.au\/?p=45710\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Delonix Bioworks Announces First Participant Dosed in Phase 1 Clinical Trial of Next-Generation MenB OMV Vaccine DX-104 in China - My Blog\" \/>\n<meta property=\"og:description\" content=\"SHANGHAI, July 13, 2026 \/PRNewswire\/ — Delonix Bioworks, a clinical-stage biotechnology company pioneering genetically engineered bacterial vaccines, today announced that the first participant has been dosed in its Phase 1 clinical trial of DX-104 in China. 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