{"id":7832,"date":"2022-04-04T09:10:00","date_gmt":"2022-04-04T09:10:00","guid":{"rendered":"https:\/\/www.prnasia.com\/story\/archive\/3712685_AE12685_0"},"modified":"2022-04-04T09:10:00","modified_gmt":"2022-04-04T09:10:00","slug":"ascletis-announces-completion-of-first-sale-of-its-ritonavir-tablets-in-zhejiang-province","status":"publish","type":"post","link":"https:\/\/transmediavictoria.net.au\/?p=7832","title":{"rendered":"Ascletis Announces Completion of First Sale of Its Ritonavir Tablets in Zhejiang Province"},"content":{"rendered":"<div><img decoding=\"async\" src=\"https:\/\/en.prnasia.com\/prnasia.com-PC\/images\/logo-en-blue-in.png\" class=\"ff-og-image-inserted\"><\/div>\n<p><span class=\"xn-location\">HANGZHOU<\/span>, China&nbsp;and SHAOXING, <span class=\"xn-location\">China<\/span>, <span class=\"xn-chron\">April 4, 2022<\/span> \/PRNewswire\/ &#8212; Ascletis Pharma Inc. (HKEX: 1672) today announces that the first sale of its ritonavir tablets in <span class=\"xn-location\">Zhejiang Province<\/span> has been completed.<\/p>\n<p>On <span class=\"xn-chron\">April 3, 2022<\/span>, Ascletis&#8217; distributor, Zhejiang Int&#8217;l Medicine Co., Ltd. (&#8220;Zhejiang Int&#8217;l&#8221;), completed the first sale of Ascletis&#8217; ritonavir tablets in <span class=\"xn-location\">Zhejiang Province<\/span>. Zhejiang Int&#8217;l is a major company engaged in the wholesale and retail of pharmaceuticals and medical equipment in <span class=\"xn-location\">Zhejiang Province<\/span>.<\/p>\n<p>As a leading antiviral company in <span class=\"xn-location\">China<\/span>, to date, Ascletis owns the only authorized ritonavir tablet in <span class=\"xn-location\">China<\/span>, which has passed bioequivalence study. Ascletis&#8217; ritonavir tablet was approved in <span class=\"xn-chron\">September 2021<\/span> by China National Medical Products Administration (\u56fd\u836f\u51c6\u5b57 H20213698).<\/p>\n<p>Ritonavir tablet is a pharmacokinetic booster of multiple oral antiviral drugs targeting viral proteases. <i>Diagnosis and Treatment Protocol for Novel Coronavirus Pneumonia (Trial Version 9) <\/i>released on <span class=\"xn-chron\">March 15, 2022<\/span> by the National Health Commission of <span class=\"xn-location\">the People&#8217;s Republic of China<\/span> includes PF-07321332\/ritonavir (Paxlovid) as an antiviral therapy for COVID-19.<\/p>\n<p>Ascletis has further expanded its ritonavir tablet production capacity to approximately 530 million tablets per year to secure the supplies. Ascletis has submitted marketing authorization applications for ritonavir (100 mg film-coated tablet) in 12 European countries (<span class=\"xn-location\">Germany<\/span>, <span class=\"xn-location\">France<\/span>, <span class=\"xn-location\">Ireland<\/span>, the <span class=\"xn-location\">United Kingdom<\/span>, <span class=\"xn-location\">Spain<\/span>, <span class=\"xn-location\">Portugal<\/span>, <span class=\"xn-location\">Italy<\/span>, <span class=\"xn-location\">Belgium<\/span>, <span class=\"xn-location\">Poland<\/span>, <span class=\"xn-location\">Sweden<\/span>, <span class=\"xn-location\">the Netherlands<\/span> and <span class=\"xn-location\">Denmark<\/span>) and <span class=\"xn-location\">Hong Kong, China<\/span>.<\/p>\n<p>Dr. <span class=\"xn-person\">Jinzi J. Wu<\/span>, Founder, Chairman and CEO of Ascletis, said, &#8220;It&#8217;s a great pleasure that the first sale of Ascletis&#8217; ritonavir tablets in <span class=\"xn-location\">Zhejiang Province<\/span> has been completed. Ascletis&#8217; antiviral pipeline includes two novel oral drug candidates against COVID-19, ASC10 (targeting RNA dependent RNA polymerase (RdRp)) and ASC11 (targeting 3-chymotrypsin like protease (3CLpro)), with global intellectual property. We hope to contribute to &#8216;Healthy Zhejiang&#8217; and &#8216;Healthy China&#8217; as well as the fights against COVID-19 and other infectious diseases.&#8221;<\/p>\n<p>About Ascletis<\/p>\n<p>Ascletis is an innovative R&amp;D driven biotech listed on the Hong Kong Stock Exchange (1672.HK), a global platform covering the entire value chain from discovery and development to manufacturing and commercialization. Ascletis is committed to developing and commercializing innovative drugs in the areas of viral diseases, NASH\/PBC, and cancer (oral cancer metabolic checkpoint and immune checkpoint inhibitors) to address unmet medical needs both in <span class=\"xn-location\">China<\/span> and globally. Led by a management team with deep expertise and a proven track record, Ascletis targets those therapeutic areas with unmet medical needs from a global perspective, and efficiently advances the developments of pipelines with an aim of leading in global competition. To date, Ascletis has three marketed products and 20 robust R&amp;D pipelines of drug candidates with global competitiveness, and is actively exploring new therapeutic areas.<\/p>\n<p>1. Viral Diseases: (1) Hepatitis B Virus (functional cure): focus on breakthrough therapies for CHB functional cure with a subcutaneously-injected PD-L1 antibody \u2013 ASC22 and Pegasys\u00ae as cornerstone drugs. (2) COVID-19 pipeline: currently includes (i) ritonavir oral tablet (100 mg), an authorized product, (ii) ASC10, an oral RNA dependent RNA polymerase (RdRp) inhibitor and (iii) ASC11, an oral 3-chymotrypsin like protease (3CLpro) inhibitor. (3) HIV\/AIDS: ASC22, an immune therapy to restore HIV-specific immune responses and eventually lead to a functional cure of HIV-infected patients. (4) Hepatitis C: successfully launched an all-oral regimen of combining ASCLEVIR\u00ae and GANOVO\u00ae (RDV\/DNV regimen). <br \/>2. Non-alcoholic Steatohepatitis\/Primary Biliary Cholangitis: Gannex, a wholly-owned company of Ascletis, is dedicated to the R&amp;D and commercialization of new drugs in the field of NASH. Gannex has three clinical stage drug candidates against three different targets \u2013 FASN, THR\u03b2 and FXR, three fixed-dose combinations for NASH and one PBC program targeting FXR.<br \/>3. Cancer (oral cancer metabolic checkpoint and immune checkpoint inhibitors): a pipeline of oral inhibitors targeting FASN, which plays a key role in cancer lipid metabolism, and a pipeline of oral PD-L1 small molecule next generation immune checkpoint inhibitors.<br \/>4. Exploratory Indications: Acne: Following NASH and recurrent GBM, the third indication for ASC40 has been approved to enter Phase 2 clinical trial. For more information, please visit <a target=\"_blank\" href=\"http:\/\/www.ascletis.com\/\" rel=\"nofollow noopener\">www.ascletis.com<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>HANGZHOU, China&nbsp;and SHAOXING, China, April 4, 2022 \/PRNewswire\/ &#8212; Ascletis Pharma Inc. (HKEX: 1672) today announces that the first sale of its ritonavir tablets in Zhejiang Province has been completed. On April 3, 2022, Ascletis&#8217; distributor, Zhejiang Int&#8217;l Medicine Co., Ltd. (&#8220;Zhejiang Int&#8217;l&#8221;), completed the first sale of Ascletis&#8217; ritonavir tablets in Zhejiang Province. Zhejiang [&hellip;]<\/p>\n","protected":false},"author":8,"featured_media":7833,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"class_list":["post-7832","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-business-news"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.9 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Ascletis Announces Completion of First Sale of Its Ritonavir Tablets in Zhejiang Province - My Blog<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/transmediavictoria.net.au\/?p=7832\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Ascletis Announces Completion of First Sale of Its Ritonavir Tablets in Zhejiang Province - My Blog\" \/>\n<meta property=\"og:description\" content=\"HANGZHOU, China&nbsp;and SHAOXING, China, April 4, 2022 \/PRNewswire\/ &#8212; Ascletis Pharma Inc. (HKEX: 1672) today announces that the first sale of its ritonavir tablets in Zhejiang Province has been completed. On April 3, 2022, Ascletis&#8217; distributor, Zhejiang Int&#8217;l Medicine Co., Ltd. (&#8220;Zhejiang Int&#8217;l&#8221;), completed the first sale of Ascletis&#8217; ritonavir tablets in Zhejiang Province. 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